Characterisation and structural analysis of glyoxylate cycle enzymes of Teladorsagia circumcincta
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چکیده
منابع مشابه
Selection and characterisation of monepantel resistance in Teladorsagia circumcincta isolates
Monepantel (MPTL) is one of two new anthelmintic compounds introduced onto the sheep market to control gastro-intestinal nematodes. Resistance to this compound is rare but has been reported. In order to preserve the efficacy of this and other anthelmintics, it is essential to understand both (a) the mechanisms involved in the selection of resistance and (b) how the parasites evolve to deal with...
متن کاملEnzymes of the Glyoxylate Cycle in Germinating
of conversion of fat to carbohydrate in germinating castor beans. Of the four requisite enzymes, isocitritase (Equation 3) has been demonstrated by direct assay (l), while the presence of condensing enzyme (Equation 1), aconitase (Equation 2), and malate synthetase activity (Equation 4) has been inferred from isotope incorporation data. The rates of condensing enzyme and malate synthetase, as e...
متن کاملA preliminary proteomic characterisation of extracellular vesicles released by the ovine parasitic nematode, Teladorsagia circumcincta
Teladorsagia circumcincta is a major cause of ovine parasitic gastroenteritis in temperate climatic regions. The development of high levels of anthelmintic resistance in this nematode species challenges its future control. Recent research indicates that many parasite species release extracellular vesicles into their environment, many of which have been classified as endocytic in origin, termed ...
متن کاملUrea Output by L3 Teladorsagia circumcincta and some Properties of Two Urea Producing Enzymes
BACKGROUND Like several other parasites, Teladorsagia circumcincta secretes or excretes urea, but neither the rate of efflux nor the possible metabolic sources of the urea has been considered. METHODS Parasites were maintained by passage through sheep. Urea efflux was measured using phenol/hypochlorite after treatment with urea aminohydrolase. The kinetics of creatine amidinohydrolase and arg...
متن کاملurea output by l3 teladorsagia circumcincta and some properties of two urea producing enzymes.
background: like several other parasites, teladorsagia circumcincta secretes or excretes urea, but nei-ther the rate of efflux nor the possible metabolic sources of the urea has been considered. methods: parasites were maintained by passage through sheep. urea efflux was measured using phe-nol/hypochlorite after treatment with urea aminohydrolase. the kinetics of creatine amidinohy-drolase and ...
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ژورنال
عنوان ژورنال: Molecular and Biochemical Parasitology
سال: 2020
ISSN: 0166-6851
DOI: 10.1016/j.molbiopara.2020.111335